Management of Uremic Xerosis and Chronic Kidney Disease (CKD)-Associated Pruritus (CKD-ap) With Topical Preparations: A Systematic Review and Implications in the Indian Context

Uremic xerosis and chronic kidney disease (CKD)-associated pruritus (CKD-ap) are the most commonly occurring dermatological problems faced by of CKD patients on hemodialysis which not only annoying draining to but also have an intense effect patients' quality life. The PubMed, Scopus, Google Scholar, Web Science databases were searched for literature with following search terms: uremic OR CKD-ap AND topical therapy ointment natural oil from year 2002 -2022, finally, 22 articles chosen write this review. Out studies, six used pharmacological preparations remaining 16 studies oils components. All experimental (Pre/Quazi/RCT/True experimental) focusing managing itch associated application. agents tried in various research effective CKD. They safe, easy use, without allergic reactions. Natural like almond, chia seed, clove, glycerin, paraffin, virgin coconut readily available home-care settings can be as a nurse-led intervention. Topical effective, apply large body surface areas systematic side effects. oil-based cost-effective, use.